Alternative Names:

Agammaglobulinaemia tyrosine kinase; AGMX1; ATK; B cell progenitor kinase; BPK; Bruton's tyrosine kinase; EC 2.7.10.2; kinase Btk; Kinase EMB;

Application:

WB IP

Reactivity:

Human

Dilution:

WB 1:1000~1:2000 IP 1:20

	Western blot analysis of Phospho-BTK (Y223) expression in Raji cell lysate treated with pervanadate.

Purification:

Affinity-chromatography

Specificity:

Phospho-BTK (Y223) Antibody detects endogenous levels of total Phospho-BTK (Y223)

Immunogen:

A synthesized peptide derived from human Phospho-BTK (Y223)

Description:

Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.