Alternative Names:

PHA; LMN2R; TDRD18; DHCR14B; LBR;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:30

	Western blot analysis of Lamin B Receptor expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

Lamin B Receptor Antibodydetects endogenous levels of total Lamin B Receptor

Immunogen:

A synthesized peptide derived from human Lamin B Receptor

Description:

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.