Alternative Names:

BDNF;MGC34632;Abrineurin; ANON2; Brain Derived Neurotrophic Factor; Neurotrophin;BULN2;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of extracts of Mouse heart lysate, using BDNF antibody
	Immunohistochemical analysis of paraffin-embedded human brain, using BDNF Antibody.
	Immunofluorescent analysis of Hela cells, using BDNF Antibody.

Purification:

Affinity-chromatography

Specificity:

BDNF Antibody detects endogenous levels of BDNF

Immunogen:

A synthesized peptide derived from human BDNF

Description:

Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.