Alternative Names:

HTRA2; HtrA-like serine protease; OMI; PARK13; Protease; PRSS25; Serine protease 25; HtrA serine peptidase 2; Serine proteinase OMI;

Application:

WB IHC IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:30

	Western blot analysis of HTRA2 expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

HTRA2 Antibody detects endogenous levels of HTRA2

Immunogen:

A synthesized peptide derived from human HTRA2

Description:

High temperature requirement protein A2 (HtrA2)/Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified to be present in either the nucleus or endoplasmic reticulum, subsequent studies have shown that it localizes in mitochondria and is released during apoptosis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.