Alternative Names:

Isl-1; ISLET1; Islet1; ISL 1;

Application:

WB ICC/IF IP

Reactivity:

Human Mouse

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of Islet 1 expression in K562 cell lysate.

Purification:

Affinity-chromatography

Specificity:

Islet 1 Antibody detects endogenous levels of Islet 1

Immunogen:

A synthesized peptide derived from human Islet 1

Description:

ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.