Alternative Names:

FTH1; Ferritin heavy chain; Ferritin heavy polypeptide 1; FHC; FTHL6; PIG15; PLIF; FTH;

Application:

WB ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:200

	Western blot analysis of Ferritin expression in Jurkat cell lysate.
	Immunofluorescent analysis of Jurkat cells, using Ferritin Antibody.

Purification:

Affinity-chromatography

Specificity:

Ferritin Antibody detects endogenous levels of Ferritin

Immunogen:

A synthesized peptide derived from human Ferritin

Description:

The assembled ferritin molecule, often referred to as a nanocage, can store up to 4,500 atoms of iron. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits made up of two types of polypeptide chains: ferritin heavy chain and ferritin light chain, each having unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.