Alternative Names:

MYL2; MLC2; Myosin light chain 2; MLC-2; RLC of myosin; CMH10; MLC-2v;

Application:

WB IHC IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:5000 IHC 1:50~1:200 IP 1:50

	Western blot analysis of Myosin Light Chain 2 expression in Mouse heart lysate.
	Immunohistochemical analysis of paraffin-embedded human heart, using Myosin Light Chain 2 Antibody.

Purification:

Affinity-chromatography

Specificity:

Myosin Light Chain 2 Antibody detects endogenous levels of Myosin Light Chain 2

Immunogen:

A synthesized peptide derived from human Myosin Light Chain 2

Description:

Myosin is composed of six polypeptide chains: two identical heavy chains and two pairs of light chains. Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC), RLC, or LC20, has many isoforms depending on its distribution. In smooth muscle, MLC2 is phosphorylated at Thr18 and Ser19 by myosin light chain kinase (MLCK) in a Ca2+/calmodulin-dependent manner.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.