Alternative Names:

VAV2; Vav 2 oncogene; VAV-2;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:100

	Western blot analysis of VAV2 expression in 293T cell lysate.
	Immunohistochemical analysis of paraffin-embedded human breast cancer, using VAV2 Antibody.

Purification:

Affinity-chromatography

Specificity:

VAV2 Antibody detects endogenous levels of VAV2

Immunogen:

A synthesized peptide derived from human VAV2

Description:

Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.