Alternative Names:

JAG1; AGS; AHD; Alagille syndrome; CD339 antigen; HJ1; Jagged1; JAGL1; Jagged; Jagged 1; Protein jagged-1; AWS; CD339; Soluble protein jagged;

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200

	Western blot analysis of JAG1 expression in HepG2 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human kidney, using JAG1 Antibody.

Purification:

Affinity-chromatography

Specificity:

JAG1 Antibody detects endogenous levels of JAG1

Immunogen:

A synthesized peptide derived from human JAG1

Description:

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.