Alternative Names:

E3 ubiquitin protein ligase NEDD4 like protein; KIAA0439; NEDD4 2; NEDD4 2c; Nedd4-2; NEDD4-2a; NEDD4b; NEDD4L; NEDL3; RSP5;

Application:

WB IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:20000 IP 1:50

	Western blot analysis of NEDD4-2 expression in (1) K562 cell lysate; (2) HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

NEDD4-2 Antibody detects endogenous levels of NEDD4-2

Immunogen:

A synthesized peptide derived from human NEDD4-2

Description:

NEDD4 was originally identified as a gene that is highly expressed in the early mouse embryonic central nervous system. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.