Alternative Names:

Apoptotic protease Mch4; CASP10; Caspase 10; FLICE2; ICE like apoptotic protease 4; FADD-like ICE2;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:10 FC 1:50

	Western blot analysis of pro Caspase 10 expression in HeLa cell lysate.
	Immunofluorescent analysis of MCF-7 cells, using pro Caspase 10 Antibody.

Purification:

Affinity-chromatography

Specificity:

pro Caspase 10 Antibody detects endogenous levels of pro Caspase 10

Immunogen:

A synthesized peptide derived from human pro Caspase 10

Description:

Caspases are a family of cytosolic aspartate specific cysteine proteases. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaved Caspase 10 leads to the processing of Caspase 3 and Caspase 7, initiating a caspase cascade and subsequent apoptosis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.