Alternative Names:

Cdc2 related protein kinase; Cyclin-dependent kinase 2; CDC28; Cell division protein kinase 2; p33 protein kinase; CDK2; CDKN2; CDC2A;

Application:

WB IHC IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 IP 1:50

	Western blot analysis of Phospho-CDK2 (Y15) expression in (1) HeLa treated with AP; (2) HeLa cell lysate.
	Immunohistochemical analysis of paraffin-embedded human bladder cancer, using Phospho-CDK2 (Y15) Antibody.

Purification:

Affinity-chromatography

Specificity:

Phospho-CDK2 (Y15) Antibody detects endogenous levels of Phospho-CDK2 (Y15)

Immunogen:

A synthesized peptide derived from human CDK2

Description:

CDK2 is an important component of the cell cycle machinery. Like p34cdc2, kinase activity is regulated by phosphorylation state as well as association with a cyclin subunit and a CDK inhibitor. This protein can be regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.