Alternative Names:

Apopain; CASP-3; CASP3; Caspase-3 subunit p12; CPP-32; Cysteine protease CPP32; Protein Yama; SCA-1; SREBP cleavage activity 1;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:1000 IHC 1:100~1:500 ICC/IF 1:50~1:200

	Western blot analysis of Caspase-3 p12 expression in HeLa cell treated with staurosporine lysate.
	Immunohistochemical analysis of paraffin-embedded human kidney, using Caspase-3 p12 Antibody.
	Immunofluorescent analysis of HeLa cells, using Caspase-3 p12 Antibody.

Purification:

Affinity-chromatography

Specificity:

Caspase-3 p12 Antibody detects endogenous levels of Caspase-3 p12

Immunogen:

A synthesized peptide derived from human Caspase-3 p12

Description:

Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). Involved in the activation cascade of caspases responsible for apoptosis execution.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.