Alternative Names:

BR; CD 49b; CD49 antigen like family member B; Collagen receptor; GPIa; HPA5; ITGA2; Platelet glycoprotein GPIa; VLA 2 alpha chain;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:100 FC 1:100

	Western blot analysis of Integrin alpha 2 expression in A431 cell lysate.

Purification:

Affinity-chromatography

Specificity:

Integrin alpha 2 Antibody detects endogenous levels of Integrin alpha 2

Immunogen:

A synthesized peptide derived from human Integrin alpha 2

Description:

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.