Alternative Names:

DIRA; ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); Interleukin-1 receptor antagonist protein; IRAP; Type II interleukin 1 receptor antagonist;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:20000 IHC 1:50~1:200 ICC 1:50~1:200 FC 1:50 IP 1:50

	Western blot analysis of IL1RA expression in (1) HeLa cell lysate; (2) 3T3 cell lysate.

Purification:

Affinity-chromatography

Specificity:

IL1RA Antibody detects endogenous levels of IL1RA

Immunogen:

A synthesized peptide derived from human IL1RA

Description:

Interleukin-1 (IL-1) is a key pro-inflammatory cytokine that has diverse actions in the brain as a regulator of host defense responses and a mediator of inflammation. Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.