Alternative Names:

Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; GluRA; GluRK1; Glutamate receptor ionotropic, AMPA 1; GluA1; GRIA1; GLUH1; GLUR1;

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:1000

	Western blot analysis of Phospho-GluR1 (S845) expression in (1) Human brain lysate treated with Lambda phosphatase lysate; (2) Human brain lysate.

Purification:

Affinity-chromatography

Specificity:

Phospho-GluR1 (S845) Antibody detects endogenous levels of Phospho-GluR1 (S845)

Immunogen:

A synthesized peptide derived from human GluR1

Description:

AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.