Alternative Names:

CD220; HHF5; human insulin receptor; Insr; Insulin receptor subunit beta; IR 1; IR;

Application:

WB ICC/IF

Reactivity:

Human Rat

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200

	Western blot analysis of Insulin Receptor expression in HeLa cell lysate.
	Immunofluorescent analysis of BxPC-3 cells, using Insulin Receptor Antibody.

Purification:

Affinity-chromatography

Specificity:

Insulin Receptor Antibody detects endogenous levels of Insulin Receptor

Immunogen:

A synthesized peptide derived from human Insulin Receptor

Description:

Insulin Receptor is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues; Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.