Alternative Names:

CMT2B; PRO2706; PSN; RAB7, member RAS oncogene family; RAB7A; RAB7A, member RAS oncogene family; Ras associated protein RAB7; Ras related protein Rab7a;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of RAB7 expression in (1) A375 cell lysate; (2) 3T3 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human colon, using RAB7 Antibody.
	Immunofluorescent analysis of Hela cells, using RAB7 Antibody.

Purification:

Affinity-chromatography

Specificity:

RAB7 Antibody detects endogenous levels of RAB7

Immunogen:

A synthesized peptide derived from human RAB7

Description:

Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.