Alternative Names:

apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CASP-7; Caspase-7 subunit p11; CMH-1; ICE-LAP3; ICE-like apoptotic protease 3;

Application:

WB IHC ICC/IF

Reactivity:

Human

Dilution:

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of pro Caspase 7 expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

pro Caspase 7 Antibody detects endogenous levels of pro Caspase 7

Immunogen:

A synthesized peptide derived from human pro Caspase 7

Description:

Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.