Alternative Names:

Phosphatase and tensin homolog; PTEN; MMAC1; TEP1;

Application:

WB ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200

	Western blot analysis of Phospho-PTEN (S380) expression in (1) MCF-7 cell treated with alkaline phosphatase lysate; (2) MCF-7 cell lysate.

Purification:

Affinity-chromatography

Specificity:

Phospho-PTEN (S380) Antibody detects endogenous levels of Phospho-PTEN (S380)

Immunogen:

A synthesized peptide derived from human PTEN

Description:

PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN regulates p53 protein levels and activity (8) and is involved in G protein-coupled signaling during chemotaxis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.