Alternative Names:

14 3 3 protein; Epithelial cell marker protein 1; HME 1; Mkrn3; Mme1; SFN protein; Stratifin; YWHAS;

Application:

WB IHC

Reactivity:

Human Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200

	Western blot analysis of 14-3-3 sigma expression in A431 cell lysate.

Purification:

Affinity-chromatography

Specificity:

14-3-3 sigma Antibody detects endogenous levels of 14-3-3 sigma

Immunogen:

A synthesized peptide derived from human 14-3-3 sigma

Description:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.