Alternative Names:

CANDF7; ISGF 3 ; Signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription 1-alpha/beta; Stat1; STAT91; Transcription factor ISGF-3 components p91/p84;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human

Dilution:

WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:500

	Western blot analysis of STAT1 alpha expression in Hela cell lysate.

Purification:

Affinity-chromatography

Specificity:

STAT1 alpha Antibody detects endogenous levels of STAT1 alpha

Immunogen:

A synthesized peptide derived from human STAT1 alpha

Description:

The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ. Phosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation, and DNA binding. The inappropriate activation of Stat1 occurs in many tumors.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.