Alternative Names:

MAP2K5; HsT17454; MAPKK 5; MEK 5; MAPKK5; MEK5; MKK5; MAP kinase kinase 5; PRKMK5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200

	Western blot analysis of MEK5 expression in Hela cell lysate.

Purification:

Affinity-chromatography

Specificity:

MEK5 Antibody detects endogenous levels of MEK5

Immunogen:

A synthesized peptide derived from human MEK5

Description:

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.