Alternative Names:

Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6; AN2;

Application:

WB IHC FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 FC 1:500

	Western blot analysis of PAX6 expression in HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

PAX6 Antibody detects endogenous levels of PAX6

Immunogen:

A synthesized peptide derived from human PAX6

Description:

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.