Alternative Names:

GOK; SIM; STIM 1; Stim1 stromal interaction molecule 1; STIM1L; Stromal interaction molecule 1;

Application:

WB IHC IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 IP 1:50

	Western blot analysis of Stromal interaction molecule 1 expression in HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

Stromal interaction molecule 1 Antibody detects endogenous levels of Stromal interaction molecule 1

Immunogen:

A synthesized peptide derived from human Stromal interaction molecule 1

Description:

STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.