Alternative Names:

5'-AMP-activated protein kinase catalytic subunit alpha-2; ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK alpha 2 chain; AMPK subunit alpha-2; AMPK2; AMPKalpha2; PRKAA2;

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000

	Western blot analysis of AMPK beta 1 expression in (1) 293T cell lysate treated with Lambda lysate; (2) 293T cell lysate.

Purification:

Affinity-chromatography

Specificity:

Phospho-AMPK alpha 2 (S491) Antibody detects endogenous levels of Phospho-AMPK alpha 2 (S491)

Immunogen:

A synthesized peptide derived from human AMPK alpha 2

Description:

AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.