Alternative Names:

Mitogen-activated protein kinase 10; MAP kinase 10; MAPK 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; MAPK10; JNK3; JNK3A; PRKM10; SAPK1B;

Application:

WB ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200 FC 1:500

	Western blot analysis of JNK3 expression in HeLa lysate.

Purification:

Affinity-chromatography

Specificity:

JNK3 Antibody detects endogenous levels of JNK3

Immunogen:

A synthesized peptide derived from human JNK3

Description:

The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, growth factors and GPCR agonists. Plays regulatory roles in the signaling pathways during neuronal apoptosis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.