Alternative Names:

CANDF7; ISGF 3; Signal transducer and activator of transcription 1; Stat1; STAT91; Transcription factor ISGF-3 components p91/p84;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:1000~1:2000

	Western blot analysis of Phospho-STAT1 (Y701) expression in (1) A431 cell lysate; (2) A431 lysate cell treated with EGF.

Purification:

Affinity-chromatography

Specificity:

Phospho-STAT1 (Y701) Antibody detects endogenous levels of Phospho-STAT1 (Y701)

Immunogen:

A synthesized peptide derived from human STAT1

Description:

The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ. Stat1 protein exists as a pair of isoforms, Stat1α (91 kDa) and the splice variant Stat1β (84 kDa). In most cells, both isoforms are activated by IFN-α, but only Stat1α is activated by IFN-γ. The inappropriate activation of Stat1 occurs in many tumors.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.