Alternative Names:

14 3 3 protein beta; 14 3 3 protein beta/alpha; 14 3 3 protein zeta; 14 3 3 zeta; GW128; HS1; KCIP 1; N-terminally processed; YWHAB; YWHAD; YWHAZ;

Application:

WB IHC FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:1000 IHC 1:50~1:200 FC 1:50

	Western blot analysis of 14-3-3 expression in Hela lysate.
	Immunohistochemical analysis of paraffin-embedded human breast cancer, using 14-3-3 Antibody.

Purification:

Affinity-chromatography

Specificity:

14-3-3 Antibody detects endogenous levels of 14-3-3

Immunogen:

A synthesized peptide derived from human 14-3-3

Description:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.