Alternative Names:

HSPA4; APG-2; APG2; Heat shock 70kD protein 4; Hsp70RY; HSPH2; Hsp70; HS24/P52; Heat shock 70kDa protein 4; Heat shock protein 110 kDa;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of HSPA4 expression in HepG2 cell lysate.

Purification:

Affinity-chromatography

Specificity:

HSPA4 Antibody detects endogenous levels of total HSPA4

Immunogen:

A synthesized peptide derived from human HSPA4

Description:

The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins. Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions. Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.