Alternative Names:

CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:500~1:1000

	Western blot analysis of Phospho-Rac1/Cdc42 (Ser71) expression in (1) A431 cell lysate treated with LP; (2) A431 cell lysate.

Purification:

Affinity-chromatography

Specificity:

Phospho-Rac1/Cdc42 (Ser71) Antibody detects endogenous levels of total Phospho-Rac1/Cdc42 (Ser71)

Immunogen:

A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71)

Description:

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.