Alternative Names:

c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10;

Application:

WB IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IP 1:50

	Western blot analysis of JNK1/JNK3 expression in HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

JNK1/JNK3 Antibody detects endogenous levels of total JNK1/JNK3

Immunogen:

A synthesized peptide derived from human JNK1/JNK3

Description:

The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.