Alternative Names:

Apoptotic protease Mch4; CASP10; Caspase10; FLICE2; ICE like apoptotic protease 4; FADD-like ICE2;

Application:

WB IHC IP FC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:100 IP 1:50 FC 1:50

	Western blot analysis of Caspase-10 expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

Caspase-10 Antibody detects endogenous levels of total Caspase-10

Immunogen:

A synthesized peptide derived from human Caspase-10

Description:

Caspase-10 is a DED (death effector domain)-containing caspase and functions as an initiator caspase in Fas/TNF induced apoptosis. Four isoforms of caspase-10 have been identified: caspase-10a (Mch4), caspase-10b (FLICE2), caspase-10c and caspase-10d. They have the same prodomain but different mature large and small subdomains).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.