Alternative Names:

TSG101; ESCRT-I complex subunit TSG101; Tumor susceptibility gene 10; Tumor susceptibility protein; VPS23; TSG10;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of TSG101 expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

TSG101 Antibody detects endogenous levels of total TSG101

Immunogen:

A synthesized peptide derived from human TSG101

Description:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.