Alternative Names:

CITED2; MRG1; MRG-1; MSG-related protein 1; ASD8; VSD2; MSG1-related gene 1; p35SRJ;

Application:

WB

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000

	Western blot analysis of CITED2 expression in HeLa cell lysate.

Purification:

Affinity-chromatography

Specificity:

CITED2 Antibody detects endogenous levels of total CITED2

Immunogen:

A synthesized peptide derived from human CITED2

Description:

Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.