Alternative Names:

CHET9; JJAZ1; KIAA0160; SUZ12;

Application:

WB ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of SUZ12 expression in (1) HeLa cell lysate; (2) SW480 cell lysate.

Purification:

Affinity-chromatography

Specificity:

SUZ12 Antibody detects endogenous levels of total SUZ12

Immunogen:

A synthesized peptide derived from human SUZ12

Description:

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.