Alternative Names:

GRM2; Glutamate receptor homolog; GPRC1B; MGlu2; Metabotropic; GLUR2; MGLUR2;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of mGluR2 expression in Mouse brain lysate.

Purification:

Affinity-chromatography

Specificity:

mGluR2 Antibody detects endogenous levels of total mGluR2

Immunogen:

A synthesized peptide derived from human mGluR2

Description:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.