Alternative Names:

Stromal cell-derived factor 1; SDF-1; hSDF-1; IRH; hIRH; PBSF; CXCL12; SDF1; SDF1A; SDF1B;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:1000~1:5000 ICC/IF 1:50~1:200

	Western blot analysis of SDF1 expression in Jurkat cell lysate.

Purification:

Affinity-chromatography

Specificity:

SDF1 Antibody detects endogenous levels of total SDF1

Immunogen:

A synthesized peptide derived from human SDF1

Description:

Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.