Alternative Names:

ALK tyrosine kinase receptor precursor, Anaplastic lymphoma kinase, CD246, EC 2.7.10.1, kinase ALK

Application:

WB IHC

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of ALK phosphorylation expression in anisomycin treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-ALK (Tyr1507) Antibody detects endogenous levels of ALK only when phosphorylated at Tyrosine 1507

Immunogen:

A synthesized peptide derived from human ALK around the phosphorylation site of Tyrosine 1507

Description:

a tyrosine kinase of the ALK family. Plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. Translocated and expressed as a fusion protein in anaplastic lymphoma.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.