Alternative Names:

ATX1, ATXN1, SCA1, Spinocerebellar ataxia type 1 protein, Spinocerebellar ataxia type 1 protein homolog

Application:

WB IF/ICC

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:2000 IF/ICC 1:100-1:500

	Western blot analysis of Ataxin 1 phosphorylation expression in Adriamycin treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-Ataxin 1 (Ser775) Antibody detects endogenous levels of Ataxin 1 only when phosphorylated at Serine 775

Immunogen:

A synthesized peptide derived from human Ataxin 1 around the phosphorylation site of Serine 775

Description:

ataxin-1 is a spinocerebellar ataxia type 1 (SCA1) protein. Expansion of CAG repeats in the SCA1 gene results in an abnormally long polyglutamine tract in the protein, causing polyglutamine-induced neurodegeneration.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.