Alternative Names:

CD3-zeta, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain precursor, T3Z, TCRZ

Application:

WB

Reactivity:

Human,Mouse

Dilution:

WB 1:500-1:2000

	Western blot analysis of CD3 ζ (Phospho-Tyr142) expression in Jurkat cell lysa

Purification:

Affinity-chromatography

Specificity:

CD3 ζ (Phospho-Tyr142) Antibody detects endogenous levels of total CD3 ζ (Phospho-Tyr142)

Immunogen:

A synthesized peptide derived from human CD3 ζ (Phospho-Tyr142)

Description:

Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.