Alternative Names:

EC 2.7.11.22 EC 2.7.11.23 p34 protein kinase Cyclin-dependent kinase 1 CDK1

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis of CDC2 phosphorylation expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-CDC2 (Tyr15) Antibody detects endogenous levels of CDC2 only when phosphorylated at Tyrosine 15

Immunogen:

A synthesized peptide derived from human CDC2 around the phosphorylation site of Tyrosine 15

Description:

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.