Alternative Names:

C-terminal binding protein 1; CTBP; EC 1.1.1.-

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis on Jurkat cell lysate using Phospho-CtBP1(Ser422) Antibody

Purification:

Affinity-chromatography

Specificity:

Phospho-CtBP1(Ser422) Antibody detects endogenous levels of CtBP1 only when phosphorylated at Sersine 422

Immunogen:

A synthesized peptide derived from human CtBP1 around the phosphorylation site of Sersine 422

Description:

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.