Alternative Names:

DNA- PKcs, DNA-dependent protein kinase catalytic subunit, DNPK1, EC 2.7.11.1, P460, PRKD, PRKDC, XRCC7, kinase DNA-PK

Application:

IHC IF/ICC

Reactivity:

Human

Dilution:

IHC 1:50-1:200 IF/ICC 1:100-1:500

	Western blot analysis of DNA-PK phosphorylation expression in whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-DNA-PK (Thr2647) Antibody detects endogenous levels of DNA-PK only when phosphorylated at Threonine 2647

Immunogen:

A synthesized peptide derived from human DNA-PK around the phosphorylation site of Threonine 2647

Description:

The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.