Alternative Names:

CRMP2, Collapsin response mediator protein 2, DPYL2, DPYSL2, DRP-2, Dihydropyrimidinase related protein-2, N2A3, TOAD-64, Turned on after division, 64 kDa protein, ULIP 2 protein, ULIP2

Application:

WB IHC IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

	Western blot analysis of DRP-2 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-DRP-2 (Thr514) Antibody detects endogenous levels of DRP-2 only when phosphorylated at Threonine 514

Immunogen:

A synthesized peptide derived from human DRP-2 around the phosphorylation site of Threonine 514

Description:

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.