Alternative Names:

IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:500~1:1000

	Western blot analysis of IL23 expression in Raji cell lysate.

Purification:

Affinity-chromatography

Specificity:

IL23 Antibody detects endogenous levels of total IL23

Immunogen:

A synthesized peptide derived from human IL23

Description:

Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.