Alternative Names:

Dip1; LVNC7; MIB; mib1; ZZANK2; ZZZ6;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of MIB1 / DIP1 expression in Caco2 cell lysate.

Purification:

Affinity-chromatography

Specificity:

MIB1 / DIP1 Antibody detects endogenous levels of total MIB1 / DIP1

Immunogen:

A synthesized peptide derived from human MIB1 / DIP1

Description:

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.