Alternative Names:

HIWI; MIWI; PIWI; PIWIL1;

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000

	Western blot analysis of PIWIL1 expression in HepG2 cell lysate.

Purification:

Affinity-chromatography

Specificity:

PIWIL1 Antibody detects endogenous levels of total PIWIL1

Immunogen:

A synthesized peptide derived from human PIWIL1

Description:

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.